Excess estradiol in men – is your prostate enlarged?

High estradiol levels in men can result in increased proliferation of the prostate gland and a condition called prostatic hypertrophy or “enlarged prostate”.  High estrogen levels have been associated with myocardial infarction.  This causes difficulties in urination.  This becomes more prominent as men grow older.  Testosterone levels decrease and the relative increase in estrogen to testosterone gives the effect of excess estrogen.  Testosterone gets converted to estrogen via aromatase activity or DHT via 5-alpha-reductase activity.

     There are several things a man can do to lower high estradiol levels:

– Reduce alcohol intake to one serving per day (or discontinue alcohol consumption)

– Reduce coffee intake to two or less servings per day

– Increase animal protein intake.  This increases the 5-alpha-reductase activity and keeps the testosterone to estradiol conversion from predominating.  Consuming Meat, Soy, cruciferous vegetables, shellfish, resveratrol, vitamins C and K, zinc, and niacin are recommended to lower estradiol levels.  Supplemental I3C or DIM are helpful in metabolizing excess estrogen.

– Keep weight down.  Increased weight (increased fat mass) leads to increase in aromatase activity that converts testosterone to estradiol.

– Tight underwear increases the temperature of the testes and reduces testosterone production and increases estradiol production.

– Hyperthyroidism converts more testosterone to estradiol.  Hypothyroidism leads to weight gain and more estradiol production in the fat cells as described above.

– Some drugs lower androgens (testosterone).  These include warfarin, beta-blockers, calcium channel-blockers, amiodarone and quinidine.  Other drugs compete with testosterone receptors like spironolactone and thiazide diuretics.

– Low Cortisol lead to more estradiol production by contributing to testicular insufficiency.

– If your partner is taking topical estrogen therapy, be mindful of transfer to your skin.

Some of these actions can also reduce sex hormone binding globulin(shbg) .  This is the blood’s major testosterone binding protein and can tie up much of a man’s testosterone – leading to reduced testosterone activity.

     If you suspect enlarged prostate and would like to explore these treatment options or test for salivary hormone levels, let us know and we can help!








12 responses to “Excess estradiol in men – is your prostate enlarged?”

  1. Mike Stegenga Avatar

    Very interesting I agree, my testosterone is horrible doctors no help.so I started doing everything you said incredible results . But really need to get dailed in.Thank you

  2. […] of the most cumbersome factors of having too much estrogen is that it increases the size of the prostate. This significant increase in prostate size affects its function and ultimately increases the […]

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  4. […] Excess estradiol in men – is your prostate enlarged? | – Mar 2, 2013. Testosterone levels decrease and the relative increase in estrogen to. There are several things a man can do to lower high estradiol levels:. If you suspect enlarged prostate and would like to explore these treatment. […]

  5. Suvendu Avatar

    I have been diagnosed with Grade 1 prostatomegaly.Had lower abdomen pain.Have taken Alfuzosin for three months.Results were temporary.Symtoms have returned.

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  7. Mamydziecko.Com Avatar

    Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at high doses.

  8. Jo Avatar

    Yes, I have an enlarged prostate and I’m looking for treatment options. Over the past 6 years, estradiol increased from 0.30 to 0.48 and testosterone decreased from 498 to 415.

  9. shannon jorgensen Avatar
    shannon jorgensen

    Hello !
    My boyfreind is 59 and he is in extreme pain due to his prostate, maybe. I say maybe because since covid he really wont go to the doctor or hospital so prostate isnt confirmed but he has all the symptoms.
    Is there something you would recommend to relieve his issues? I am a little confused, there are so many out there, what is best?
    Thank you so much for your time, it means a great deal to me. Take care and make it a great day !

  10. micheal Ajibola Avatar
    micheal Ajibola

    i have low testorone and HBP

  11. Michael Mahr Avatar
    Michael Mahr

    I had radiation treatment for aggressive prostate cancer 16 years ago. My prostate has now enlarged and is preventing urine flow. For years I have gotten shots to eliminate 95% of my testosterone, but the cancer has gotten around that strategy, so my new meds are removing that last 5%. I am now also suffering from an enlarged prostate preventing me from urinating, so I must self catheter. I told my doctor my I thought my testosterone to estrogen ratio was causing my prostate to enlarge and she replied, “No, high testosterone levels can enlarge a prostate, not high estrogen levels.” If she is correct, why aren’t young men carrying around huge prostate and cannot urinate?

  12. Michael Pugliese Avatar
    Michael Pugliese

    I have BPH and would like help please?
    I’d like an estrogen test and Rezum treatment if you can help?

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